Determination of N-Methylpyrrolidine in Cefepime Using a Reagent-Free Ion Chromatography System
ثبت نشده
چکیده
منابع مشابه
An improved ion chromatographic method for fast and sensitive determination of N-methylpyrrolidine in cefepime hydrochloride.
An alternative ion chromatographic method to the existing USP method for the determination of N-methylpyrrolidine (NMP) in cefepime hydrochloride is developed. The cefepime in solution behaves as a strong cation and gets retained in the analytical column, leading to reduction in column capacity and irreproducible retention time. The retained drug has to be removed with a special rinsing solutio...
متن کاملApplication of Differential Kinetic Method Using ANN with a New Synthetic Reagent for Simultaneous Spectrophotometric Determination of Mercury and Palladium
A new selective reagent was used for simultaneous determination of mercury and palladium in real samples with their different kinetic spectrophotometric properties. The method is based on the difference in the rate of the oxidation reaction of the recently synthesized reagent, nitro benzoyl diphenylmethylen phosphorane (N-BDMP), with Hg2+ and Pd2+. The kinetic profiles were monitored and record...
متن کاملPreparation of second generation ionic liquids by efficient solvent-free alkylation of N-heterocycles with chloroalkanes.
Non-conventional techniques, such as microwave (MW) and power ultrasound (US) as well as combined MW/US irradiation, have been used to promote one-pot synthesis of second-generation ionic liquids (ILs), cutting down reaction times and improving yields. However, the use of chloroalkanes in the alkylation of N-heterocycles requires more drastic conditions if results are to match those obtained wi...
متن کامل